There are some effects of Audio Guided Imagery on parameters that are not primarily related to mind, as with stress, mood or pain. For example with type I diabetes in a blinded randomized study  conducted in Israel with young people with type I insulin dependent diabetes, 7 children were assigned to a group receiving an audio disc with guided imagery and other 6 received only a disc with music. They were connected to a system of continuous glucose monitoring and came daily to the clinic to listen to the CD twice a day for 4 days and then they were disconnected from the system. Participants heard the discs for 11 weeks every day and later they were also re-evaluated. Glucose levels decreased in both groups but the glycosylated hemoglobin test, that measures average blood glucose levels over the past three months only decreased in the Audio Guided Imagery group, which revealed the potential of this technique to improve glycemic control in patients with Diabetes type I.
The study concludes that Audio Guided Imagery is a potential approach for improving glycemic and glucose control in youth but larger studies are required.
 Effect of auditory guided imagery on glucose levels and on glycemic control in children with type 1 diabetes mellitus. Gelernter R, Lavi G, Yanai L, Brooks R, Bar Y, Bistrizer Z, Rachmiel M.